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Is there a correlation between vaping and oral cancer risk?


The relative safety of electronic cigarettes (e-cigarettes or e-cigs) has become a pressing issue in public discourse, with concerns mounting over the health implications associated with vaping. While many perceive e-cigarettes as a safer alternative to traditional tobacco smoking, recent studies are shedding light on potential risks that were previously overlooked.

In the realm of scientific and medical communities, discussions surrounding the benefits and drawbacks of e-cigarette vaping have been ongoing. However, a notable gap exists in our understanding of the fundamental biochemical and biological effects of e-cig aerosol and nicotine. Despite the widespread assumption that nicotine, the primary addictive component in e-cigarettes, is not a direct carcinogen in humans, new research is challenging this notion.



A recent study has revealed alarming parallels between the DNA damage incurred by e-cigarette users and that of smokers, particularly concerning changes linked to the future development of lung cancer. This finding raises significant concerns about the long-term health consequences of e-cigarette use, suggesting that vaping may not be as benign as previously believed.Traditionally, it takes over two decades for a lifelong tobacco smoker to develop cancer. Considering that e-cigarettes gained popularity just over a decade ago, it’s plausible to anticipate a similar timeline for the emergence of e-cigarette aerosol-associated human cancers. While no definitive cases of e-cigarette-related cancer have been reported thus far, hundreds of lung illnesses and numerous deaths have been attributed to e-cigarette vaping.



The potential for nicotine to damage genetic materials underscores the need for caution. While nicotine itself may not be a direct carcinogen, its ability to harm cells, albeit to a lesser extent, raises concerns about the cumulative effects of frequent e-cigarette use. Over time, this accumulation of damage within organs could reach a threshold that manifests as human pathology.

Considering the latency period for cancer development, it may take two decades or more before the full extent of e-cigarette carcinogenicity in humans becomes apparent. As such, the jury is still out on whether e-cigarettes pose a definitive cancer risk.

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Despite the uncertainties surrounding e-cigarette safety, regulatory efforts are underway to mitigate potential harm. Measures such as flavour bans, age restrictions, and product labelling requirements aim to curb youth uptake and enhance consumer awareness of associated risks.In conclusion, despite the fact that e-cigarettes were first promoted as a less harmful option to traditional smoking, new research indicates that using them may have unintended health effects, such as DNA damage that is connected to the development of cancer. Policymakers, medical professionals, and consumers must all continue to be watchful and aggressive in addressing the changing panorama of health hazards associated with e-cigarettes as research continues to be conducted.

(Article Courtesy: Dr. Niraj Bhatt, Consultant Medical Oncologist, Bhailal Amin General Hospital, Vadodara)



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