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Latest on Super Contagious Omicron Subvariant – NBC Chicago


A highly-transmissible mutation of the omicron COVID variant known as BA.5 is raising concerns globally as it continues to gain traction in several countries, sparking new waves of cases and, in some instances, hospitalizations.

The rise in case rates, even as metrics remain uncertain due to at-home COVID test availability, has sparked warnings and renewed calls for masking in some locations.

So what is it about the new variant that makes it particularly concerning and what should you be watching for?

Here’s what we know so far.

What should you know about BA.5?

As of July 2, the subvariant BA.5 was responsible for nearly 54% of COVID cases in the U.S. BA.4, a similar subvariant, accounted for nearly 17% more, according to the latest data from the Centers for Disease Control and Prevention.

David Montefiori, a professor at the Human Vaccine Institute at Duke University Medical Center, told NBC News that BA.4 and BA.5 are about three times less sensitive to neutralizing antibodies from existing COVID vaccines than the original version of the omicron variant, BA.1. Additional research suggests that BA.4 and BA.5 are four times more resistant to antibodies from vaccines than BA.2. That subvariant replaced omicron as the U.S.’s dominant version of the coronavirus in April.

The European Medicines Agency’s Marco Cavaleri told an online briefing that the BA.4 and BA.5 mutations are expected to become dominant across the continent, “likely replacing all other variants by the end of July.”

He said that while there is no evidence the variants make people more sick than earlier strains of the virus, “the increase in transmission among older age groups is starting to translate into severe disease.”

Which symptoms should you watch for?

The U.K., where BA.4 and BA.5 infections also account for the majority of recent COVID cases, reported runny nose, sore throat, headache, persistent cough and fatigue as its most common symptoms last week.

Less than one-third of people surveyed reported fevers, according to data from the Zoe COVID Symptom Study, which allows people to self-report symptoms through smartphone apps. The symptoms are consistent with those reported in the spring, when the BA.2 subvariant was dominant in the country.

An update to the COVID vaccines is needed to fight Omicron BA.4 and BA.5 subvariants that are increasing case counts now, says Dr. Uché Blackstock, an MSNBC medical contributor and head of Advancing Health Equity.

According to the University of California Davis Health, the reported symptoms of BA.5 are similar to previous COVID variants: fever, runny nose, coughing, sore throat, headaches, muscle pain and fatigue. At this point, there doesn’t appear to be a difference in the symptoms seen in BA.4 or BA.5 cases, compared to earlier omicron strains.

If you had COVID before, how protected are you from BA.5?

Francois Balloux, the director of the University College London Genetics Institute, said while BA.1 and BA.2 are “pretty different…BA.2, BA.4 and B.5 from a neutralizing antibody perspective are essentially interchangeable.”

Because of that, people who had BA.2 infections may have some protection from the latest subvariants, he said. While they spread quicker than any others, BA.4 and BA.5 haven’t been found to cause more severe disease, according to doctors.

“There’s really no clear evidence that they’re more or less likely to make people sick and cause severe illness and death,” stated Montefiori.

Dr. Nathan Grubaugh, an epidemiologist at the Yale School of Public Health, said people need to understand that variants like Omicron and BA.5 are a natural part of the progression of the virus.

“Delta was never going to be the last variant—and Omicron is not going to be the last one,” he said, according to an article on the school’s website. “As long as there is a COVID-19 outbreak somewhere in the world, there is going to be something new that emerges.”

What steps can you take to protect yourself?

The best way to prevent new variants, Grubaugh and other doctors say, is to get vaccinated and booster shots. If more people are fully vaccinated, the opportunity for the virus to spread and mutate decreases, they contend.

The European Union said Monday it’s “critical” that authorities in the 27-nation bloc consider giving second coronavirus booster shots to people between the ages of 60 and 79 years and other vulnerable people, as a new wave of the pandemic sweeps over the continent.

“With cases and hospitalizations rising again as we enter the summer period, I urge everybody to get vaccinated and boosted as quickly as possible. There is no time to lose,” European Commissioner for Health and Food Safety Stella Kyriakides said in a statement.

ECDC Director Andrea Ammon said that the new wave is being driven by the highly transmissible BA.5 mutation of the omicron variant of the…



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